The following example demonstrates how to fix the ShipCountry and ShipCity columns.

XAML
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<Grid xmlns:xcdg="http://schemas.xceed.com/wpf/xaml/datagrid">

  <Grid.Resources>

    <xcdg:DataGridCollectionViewSource x:Key="cvs_orders"

                                    Source="{Binding Source={x:Static Application.Current},

                                                      Path=Orders}"/>

  </Grid.Resources>

   <xcdg:DataGridControl x:Name="OrdersGrid"

                         ItemsSource="{Binding Source={StaticResource cvs_orders}}">

      <xcdg:DataGridControl.Columns>

         <xcdg:Column FieldName="ShipCountry" VisiblePosition="0"/>

         <xcdg:Column FieldName="ShipCity" VisiblePosition="1"/>

      </xcdg:DataGridControl.Columns>

      <xcdg:DataGridControl.View>

        <xcdg:TableView FixedColumnCount="2"/>

      </xcdg:DataGridControl.View>

   </xcdg:DataGridControl>

</Grid>
VB.NET
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dataGridControl.Columns( "ShipCountry" ).VisiblePosition = 0

dataGridControl.Columns( "ShipCity" ).VisiblePosition = 1

Dim view As New TableView()

view.FixedColumnCount = 2

dataGridControl.View = view
C#
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dataGridControl.Columns[ "ShipCountry" ].VisiblePosition = 0;

dataGridControl.Columns[ "ShipCity" ].VisiblePosition = 1;

TableView view = new TableView();

view.FixedColumnCount = 2;

dataGridControl.View = view;